1-Bromo-2-pentyne, with the chemical formula C$$_5$$H$$_7$$Br and a molecular weight of approximately 147.01 g/mol, is a colorless to pale yellow liquid that is primarily used as an intermediate in organic synthesis. It is categorized under the CAS number 16400-32-1 and is known for its reactivity due to the presence of a bromine atom attached to a carbon chain containing a triple bond. This compound serves as a precursor for various chemical reactions including the synthesis of alkynyl organometallic reagents and jasmonic acid derivatives which are important in the production of active pharmaceutical ingredients. As a reactive halogenated compound, 1-bromo-2-pentyne is incompatible with strong oxidizing agents and requires careful handling to prevent hazardous situations. The substance is often utilized in laboratories and industrial settings where precise chemical transformations are necessary.
Applications:
1.1-Bromo-2-pentyne acts as a reagent for organic and organometallic compounds.
2.It is employed in the preparation of stereochemically restricted lactone type analogs of jasmonic acids including 5-oxa-7-epi-jasmonic acid and 5-oxa-jasmonic acid.
3.The compound is used in the synthesis of various aldehydes such as 4,7-decadienal, 4,7-tridecadienal, 5,8-tetradecadienal and 6,9-dodecadienal.
4.It plays an important role in the synthesis of 5-ethyl-4-methylene-6-phenyl-3a,4,7,7a-tetrahydroisobenzofuran-1,3-dione.
